Aspartic acid, phenylalanine, and early menarche

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Restrained refinement of two crystalline forms of yeast aspartic acid and phenylalanine transfer RNA crystals.

Four transfer RNA crystals, the monoclinic and orthorhombic forms of yeast tRNA(Phe) as well as forms A and B of yeast tRNA(Asp), have been submitted to the same restrained least-squares refinement program and refined to an R factor well below 20% for about 4500 reflections between 10 and 3 A. In yeast tRNA(Asp) crystals the molecules exist as dimers with base pairings of the anticodon (AC) tri...

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Metabolism of L-aspartic acid.

Aspartic acid, like glutamic acid, occupies a central position in amino acid metabolism. In most tissues it takes part in the transamination reaction (1). In the liver and the kidney, where all amino acids undergo cleamination, the rate of this process for aspartic acid is second only to glutamic acid (2). For these reasons, one would expect the exchange of amino nitrogen of aspartic acid with ...

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The Synthesis of Aspartic Acid

No one of the methods proposed for the synthesis of aspartic acid is entirely satisfactory as a practical procedure. The synthesis, described in a recent paper (1) from this laboratory, has been utilized in preparing 50 to 60 gm. lots of recrystallized aspartic acid but even here the beginning reagents are expensive, the over-all yield is only about 30 per cent of the theoretical, and the proce...

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A series of copoly(alpha-amino acids) with varying percentages of hydrophilic (L-aspartic acid) and hydrophobic monomers (L-leucine, beta-methyl-L-aspartate, and beta-benzyl-L-aspartate) were implanted subcutaneously in rats and the macroscopic degradation behavior was studied. Three groups of materials (A,B,C) with different ranges of hydrophilicity were distinguished: A) hydrophobic materials...

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ژورنال

عنوان ژورنال: The American Journal of Clinical Nutrition

سال: 2015

ISSN: 0002-9165,1938-3207

DOI: 10.3945/ajcn.115.120857